Impaired production of mononuclear cell procoagulant activity in chronic lymphocytic leukaemia.

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Impaired production of mononuclear cell procoagulant activity in chronic lymphocytic leukaemia.

Chronic lymphocytic leukaemia (CLL) is associated with a low incidence of thrombotic complications, or disseminated intravascular coagulation (DIC), or both, despite the frequent occurrence of severe infections. We have investigated the capacity of blood mononuclear cells to produce procoagulant activity when stimulated with bacterial endotoxin in 16 patients with untreated chronic lymphocytic ...

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Chronic lymphocytic leukaemia.

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Chronic lymphocytic leukaemia (CLL)

Typically, proliferation of mature small lymphocytes of normal morphology; lymphocytes with more abundant cytoplasm may be present. When prolymphocytes are 10% or greater they are classified as 'chronic lymphocytic leukaemia-prolymphocytic leukaemia'. The main immunophenotypic features that define BCLL are: the predominant population shares B-cell markers CD19, CD20, and CD23 with the CD5 antig...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1983

ISSN: 0021-9746

DOI: 10.1136/jcp.36.1.37